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Dextromethorphan HBr
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Highly Characterized Analytical Standard

Active ingredient · Dextromethorphan family

Pharmaceutical analytical standard

Dextromethorphan HBr

Synonyms: Dextromethorphan Hydrobromide, Delsym, Antussan, Demorphan, Tusilan, Romilar, Benylin DM, Azedipamin, Orthoxicol, Tussi-Organidin, Endotussin-NN, Dimetapp DM, Naldecon-DX, Viro-Med, Cerose-DM, Tussar DM, Cough-X, Ru-Tuss Expectorant, Tylenol Cough Liquid, Tussi-Organidin DM NR, Endotussin-NN Pediatric, Robitussin Cough Calmers, Robitussin Cold & Cough, Ornex Severe Cold Formula, Robitussin Pediatric Cough, Tussi-Organidin DM-S NR, Tylenol Cold No Drowsiness, Drixoral Cough & Congestion, PediaCare Cough-Cold Formula, Drixoral Cough & Sore Throat, Contac Nighttime Cold Medicine, Contac Jr. Non-drowsy Formula, Robitussin Maximum Strength Cough, Robitussin Pediatric Night Relief, Tylenol Flu No Drowsiness Gelcaps, Robitussin Pediatric Cough & Cold, Trind-DM, Contac Severe Cold Formula Non-Drowsy, Contac Day & Night Cold/Flu Day Caplets, Contac Severe Cold Formula Maximum Strength, Creomulsion, Dextabs, Tussabron, Tuxium, BupropiDex, RoboCough, Stona, Franolyn dry, Franolyn sed, Contac coughcaps, Delsym Cough, Leader Cough, Honey Works, Beecham coughcaps, Giltuss DM, Equate Cough DM, Leader Cough DM, Meijer Cough DM, Mielim Y Mas, Careone Cough DM, Cough DM, Topcare Cough DM, Equaline Cough DM, Adult Cough Relief, Cough Relief Adult, Childrens Cough DM, Cough DM Childrens, Robitussin Tos Seca, Safrel Cough Relief, CVS Cough DM, Basic care cough DM, Rite Aid Cough DM, Cabinet Cough Relief, Dg Health Cough DM, Father Johns Medicine, Good Sense Cough DM, Cough medicine, Health Mart Cough DM, Adult Cough Relief DM, Robitussin Direct Cough, CVS Long Acting Cough, Creomulsion for Children, Giltuss Honey DM Cough, Leader childrens cough dm, Tussin Long Acting Cough, Honey Works Organic Honey, Giltuss diabetic dm, Long Acting Cough Softgels, Premier Value Tussin Cough, Signature Care Cough Relief, Walgreens childrens cough dm, RoboHBr Cough SUPPRESSANT, Basic care childrens cough dm, DRx Choice Long Acting Cough, Cough Medicine Soothing Relief, Cough Relief Cough Suppressant, Caring Mill Childrens Cough DM, Mucinex instasoothe cough, Adult Long Lasting Cough Relief, Good Neighbor Long Acting Cough, Childrens Giltuss Honey DM Cough, Amazon basic care childrens cough dm, Good Neighbor Pharmacy Cough DM ER, Mucinex Childrens Mighty Chews Cough, Tussin Long Acting Cough Readyincase, Childrens Robitussin Cough Long-acting, Premier Value Tussin Cough Long Acting, Robitussin long-acting coughgels, Creomulsion Cough Medicine Adult Formula, CVS Health COUGH SUPPRESSANT SOFTGEL, QUALITY CHOICE Long Acting Cough Softgel, CVS Daytime Cough Relief Chews-Citrus Punch, Good Neighbor Long Acting Cough Adult Tussin, ROBITUSSIN LONG-ACTING COUGH Soft CHEWS, Right Remedies Adult Long Lasting Cough Relief Softgel, Chloraseptic DM, Drixoral Cough, Hold, Methorate, Simasedan, Dormethan, Metrorat, Medicon, Tussade, Dextroramin P, Demorphine, Allfen-DM, Canfodion, Cosylan, Dormetan, Hihustan M., DXM HBr

Cat. No.
P-D079-002
CAS
125-69-9
Alternative CAS
  • 125-71-3 (free base)
  • 18609-21-7 (hydrochloride)
  • 6700-34-1 (hydrate)
  • 7487-74-3 (hydroiodide)
  • 1887136-04-0 (alternative CAS, same compound)
Formula
C18H25NO·HBr
Molecular weight
352.32 g/mol
Category
Active ingredient (API)

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Characterisation level

* Mass balance is performed on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it, for example oils and highly volatile substances, on which some of the required measurements cannot be made: in those cases the CoA states how the content was assigned.

Quantity
Talk to a specialist

We reply within 24 hours with a quote and availability. CoA and SDS with every lot.

Family: Dextromethorphan

A cough suppressant of the morphinan family, approved in the United States in 1958 for over-the-counter sale as an alternative to codeine; combined with quinidine it is also used for pseudobulbar affect.

Did you know?It is the mirror image of levomethorphan, the methyl ether of the opioid painkiller levorphanol: the prefix 'dextro' recalls that it rotates polarised light to the right.

The two levels compared

Level 1
Mass balance
Level 2
Mass balance + qNMR
Identity (IR, MS, 1H and 13C-NMR; peptides: ESI-MS, MALDI-TOF and IR)✓✓
HPLC purity (min. 95%)✓✓
Content by mass balance (min. 90%; peptides: for information only)*✓✓
Content verified by qNMR (small molecules only)·✓
Suitable to qualify it as an in-house primary standard (ICH Q7)·✓

* Mass balance is performed on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it, for example oils and highly volatile substances, on which some of the required measurements cannot be made: in those cases the CoA states how the content was assigned.

What you receive

The analytical standard

Shipped under controlled temperature when the molecule requires it.

Certificate of analysis (CoA)

For every lot: identity, purity and assay, with the supporting spectra and chromatograms.

Safety data sheet (SDS)

Sent with every order.

Tracked shipment

Follow your shipment live, from our warehouse to your lab.

More products in the Dextromethorphan family

See all 26 products in the family

Frequently asked questions

Is mass balance always performed?

Yes, on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it: for example oils and highly volatile substances, on which some measurements (such as thermogravimetry) cannot be made. In those cases the CoA states which method was used to assign the content.

Can I ask for a different quantity?

Yes. The quantities are only suggestions: choose "Other" and enter the milligrams or grams you need.

Which level should I choose?

Level 1 is enough for most routine testing. Level 2 adds an independent qNMR content value and is meant for labs that need to qualify an in-house primary standard. For peptides and similar molecules, Level 2 is not available.

When will I get the quote?

Within 24 working hours, with price, availability and delivery time.

Need a molecule you cannot find?

Custom synthesis of impurities, metabolites and labelled compounds, with the same characterisation level.