Active ingredient · Isoleucine family
Pharmaceutical analytical standardIsoleucine
Synonyms: L-Isoleucine, L-Ile, alpha-Amino-beta-methylvaleric acid, Norvaline, 3-methyl-, Valeric acid, 2-amino-3-methyl-, NSC 46708, FEMA NO. 4675, l-isoleucinum, H-Ile-OH, L-Norvaline, 3-methyl-, erythro-, Pentanoic acid, 2-amino-3-methyl-, Acetic acid, amino-sec-butyl-, FEMA No. 3295, Acetic acid, amino(1-methylpropyl)-, (R*,R*)-, Pentanoic acid, 2-amino-3-methyl-, (S-(R*,R))-, Pentanoic acid, 2-amino-3-methyl-, (2S,3S)-, H-lle-OH, NSC 9958, NSC 206282, H-Ile, Ile-OH, sec-C4H9CH(NH2)COOH, Norvaline, 3-methyl-, erythro-, Pharmakon1600-01301004, NSC 760109, alpha-Amino-beta-methylvaleric acid, (2S,3S)-
- Cat. No.
- P-I086-001
- CAS
- 73-32-5
- Alternative CAS
- 34464-35-2 (alternative CAS, same compound)
- 443-79-8 (alternative CAS, same compound)
- 1160211-67-5 (alternative CAS, same compound)
- Formula
- C6H13NO2
- Molecular weight
- 131.18 g/mol
- Category
- Active ingredient (API)
An essential branched-chain amino acid, like leucine and valine: the body cannot make it and obtains it from dietary protein. It was discovered in 1903 by the German chemist Felix Ehrlich.
Did you know?Ehrlich found it while studying beet-sugar molasses; only in 1907 did he confirm its presence in common proteins such as fibrin, egg albumin and gluten.
The two levels compared
| Level 1 Mass balance | Level 2 Mass balance + qNMR | |
|---|---|---|
| Identity (IR, MS, 1H and 13C-NMR; peptides: ESI-MS, MALDI-TOF and IR) | ✓ | ✓ |
| HPLC purity (min. 95%) | ✓ | ✓ |
| Content by mass balance (min. 90%; peptides: for information only)* | ✓ | ✓ |
| Content verified by qNMR (small molecules only) | · | ✓ |
| Suitable to qualify it as an in-house primary standard (ICH Q7) | · | ✓ |
* Mass balance is performed on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it, for example oils and highly volatile substances, on which some of the required measurements cannot be made: in those cases the CoA states how the content was assigned.
What you receive
Shipped under controlled temperature when the molecule requires it.
For every lot: identity, purity and assay, with the supporting spectra and chromatograms.
Sent with every order.
Follow your shipment live, from our warehouse to your lab.
Pharmacopoeial standards available
The official European Pharmacopoeia standards for this molecule, supplied with EDQM documentation.
- Isoleucine CRSEP I0460000
More products in the Isoleucine family
Frequently asked questions
Is mass balance always performed?
Yes, on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it: for example oils and highly volatile substances, on which some measurements (such as thermogravimetry) cannot be made. In those cases the CoA states which method was used to assign the content.
Can I ask for a different quantity?
Yes. The quantities are only suggestions: choose "Other" and enter the milligrams or grams you need.
Which level should I choose?
Level 1 is enough for most routine testing. Level 2 adds an independent qNMR content value and is meant for labs that need to qualify an in-house primary standard. For peptides and similar molecules, Level 2 is not available.
When will I get the quote?
Within 24 working hours, with price, availability and delivery time.
Need a molecule you cannot find?
Custom synthesis of impurities, metabolites and labelled compounds, with the same characterisation level.
