Active ingredientPethidine HydrochlorideCat. No. P-P068-001CAS 50-13-5
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Pharmacopoeial impurity · Pethidine family
Pharmaceutical analytical standardPethidine Hydrochloride EP Impurity C
Synonyms: Meperidine acid, 1-methyl-4-phenylpiperidine-4-carboxylic acid, Meperidinic acid, Pethidinic acid, Pethidine-intermediate C, Isonipecotic acid, 1-methyl-4-phenyl-, NSC 400459, Pethidine-intermediate-c, 1-methyl-4-phenylpiperidine-4-carboxylic acid, Meperdinic acid, DEA No. 9234, Pethidine intermediate C (1mg/ml in Acetonitrile), N-Methyl-4-phenyl-piperidin-4-carbon-saure
- Cat. No.
- P-P068-004
- CAS
- 3627-48-3
- Alternative CAS
- 100609-26-5 (hydrochloride)
- Formula
- C13H17NO2
- Molecular weight
- 219.28 g/mol
- Category
- Pharmacopoeial impurity (EP/USP)
Family: Pethidine
A fully synthetic opioid analgesic, obtained in Germany in the late 1930s and in medical use since 1943; for much of the 20th century it was one of the most prescribed opioids for acute pain.
Did you know?Chemist Otto Eisleb was studying it as a possible anticholinergic drug: it was Otto Schaumann who discovered its analgesic properties. It is the prototype of a large family of analgesics.
The two levels compared
| Level 1 Mass balance | Level 2 Mass balance + qNMR | |
|---|---|---|
| Identity (IR, MS, 1H and 13C-NMR; peptides: ESI-MS, MALDI-TOF and IR) | ✓ | ✓ |
| HPLC purity (min. 95%) | ✓ | ✓ |
| Content by mass balance (min. 90%; peptides: for information only)* | ✓ | ✓ |
| Content verified by qNMR (small molecules only) | · | ✓ |
| Suitable to qualify it as an in-house primary standard (ICH Q7) | · | ✓ |
* Mass balance is performed on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it, for example oils and highly volatile substances, on which some of the required measurements cannot be made: in those cases the CoA states how the content was assigned.
What you receive
The analytical standard
Shipped under controlled temperature when the molecule requires it.
Certificate of analysis (CoA)
For every lot: identity, purity and assay, with the supporting spectra and chromatograms.
Safety data sheet (SDS)
Sent with every order.
Tracked shipment
Follow your shipment live, from our warehouse to your lab.
More products in the Pethidine family
Active ingredientPethidine HydrochlorideCat. No. P-P068-001CAS 50-13-5
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Pharmacopoeial impurityPethidine Hydrochloride EP Impurity DCat. No. P-P068-005CAS 28030-27-5
Pharmacopoeial impurityPethidine Hydrochloride EP Impurity ECat. No. P-P068-006CAS 77-17-8
Pharmacopoeial impurityPethidine Hydrochloride EP Impurity FCat. No. P-P068-007CAS 61886-17-7
Pharmacopoeial impurityPethidine Hydrochloride EP Impurity GCat. No. P-P068-008CAS 561-76-2
Pharmacopoeial impurityPethidine Hydrochloride EP Impurity HCat. No. P-P068-009CAS 59084-08-1Frequently asked questions
Is mass balance always performed?
Yes, on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it: for example oils and highly volatile substances, on which some measurements (such as thermogravimetry) cannot be made. In those cases the CoA states which method was used to assign the content.
Can I ask for a different quantity?
Yes. The quantities are only suggestions: choose "Other" and enter the milligrams or grams you need.
Which level should I choose?
Level 1 is enough for most routine testing. Level 2 adds an independent qNMR content value and is meant for labs that need to qualify an in-house primary standard. For peptides and similar molecules, Level 2 is not available.
When will I get the quote?
Within 24 working hours, with price, availability and delivery time.
Need a molecule you cannot find?
Custom synthesis of impurities, metabolites and labelled compounds, with the same characterisation level.